Diagnóstico de producción en ganado lechero en pastoreo de un grupo ganadero de validación y transferencia de tecnología

The regionalization of framing issues for producers Livestock Group of Validation and Technology Transfer (GGAVATT) from San Jose Miahuatlán Veracruz, Mexico, under the current production of native grass prairie with mainly during the months of higher temperature have a poor performance and thus milk production declines which promotes a great use of concentrated feeds which causes an increase in production cost and less use to them. For this purpose we made a diagnosis of current conditions GGAVATT production, yielding information that helps us source and compared to determine precisely what the effect of applying the proposed alternative. We propose an alternative implementation of pastures with improved pastures needed to produce a greater amount of forage per unit area especially in the colder months.La regionalización de la problemática encuadrando a los productores del Grupo Ganadero de Validación y Transferencia de Tecnología (GGAVATT) de San José Miahuatlán Veracruz, México, bajo la actual situación de producción de praderas básicamente con gramas nativas que durante los meses de menor frío tienen un pobre desempeño y por ende la producción de leche se deteriora lo cual promueve una gran utilización de alimentos concentrados lo que provoca un incremento en el costo de producción y una menor utilidad para estos. Para dicho propósito se realizó un diagnóstico de las condiciones actuales de producción del GGAVATT, arrojando información que nos sirve de partida y de comparación para determinar con precisión cuál es el efecto de aplicar la alternativa propuesta. Se plantea como alternativa la implantación de praderas con pastos mejorados que permitan producir una mayor cantidad de forrajes por unidad de superficie sobre todo en los meses de menor temperatura

Analysis of Fine Motor Skills in Essential Tremor: Combining Neuroimaging and Handwriting Biomarkers for Early Management

Essential tremor (ET) is a highly prevalent neurological disorder characterized by action-induced tremors involving the hand, voice, head, and/or face. Importantly, hand tremor is present in nearly all forms of ET, resulting in impaired fine motor skills and diminished quality of life. To advance early diagnostic approaches for ET, automated handwriting tasks and magnetic resonance imaging (MRI) offer an opportunity to develop early essential clinical biomarkers. In this study, we present a novel approach for the early clinical diagnosis and monitoring of ET based on integrating handwriting and neuroimaging analysis. We demonstrate how the analysis of fine motor skills, as measured by an automated Archimedes’ spiral task, is correlated with neuroimaging biomarkers for ET. Together, we present a novel modeling approach that can serve as a complementary and promising support tool for the clinical diagnosis of ET and a large range of tremors.This work was supported in part by the Universidad del País Vasco/Euskal Herriko Unibertsitatea, the University of Cambridge, PPG 17/51 and GIU 092/19, the Basque government (Saiotek SA-2010/00028, ELEKIN, Engineering and Society and Bioengineering Research Groups, GIC18/136, and ELKARTEK 18/99, 20/81), ‘‘Ministerio de Ciencia e Innovación’’ (SAF201677758R), FEDER funds, DomusVi Foundation (FP18/76), and the government of Gipuzkoa (HELENA, SABRINA, DG18/14-23, DG19/29, DG20/25 projects). This work is also based upon the work from COST Actions CA18106 and CA15225, supported by COST (European Cooperation in Science and Technology)

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020.

Following its emergence in late 2019, the spread of SARS-CoV-21,2 has been tracked by phylogenetic analysis of viral genome sequences in unprecedented detail3–5. Although the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced. However, travel within Europe resumed in the summer of 2020. Here we report on a SARS-CoV-2 variant, 20E (EU1), that was identified in Spain in early summer 2020 and subsequently spread across Europe. We find no evidence that this variant has increased transmissibility, but instead demonstrate how rising incidence in Spain, resumption of travel, and lack of effective screening and containment may explain the variant’s success. Despite travel restrictions, we estimate that 20E (EU1) was introduced hundreds of times to European countries by summertime travellers, which is likely to have undermined local efforts to minimize infection with SARS-CoV-2. Our results illustrate how a variant can rapidly become dominant even in the absence of a substantial transmission advantage in favourable epidemiological settings. Genomic surveillance is critical for understanding how travel can affect transmission of SARS-CoV-2, and thus for informing future containment strategies as travel resumes. © 2021, The Author(s), under exclusive licence to Springer Nature Limited

SN 2014J at M82 - I. A middle-class Type Ia supernova by all spectroscopic metrics

13 págs.; 10 figs.; 4 tabs.We present the intensive spectroscopic follow up of the Type Ia supernova (SN Ia) 2014J in the starburst galaxy M82. Twenty-seven optical spectra have been acquired from 2014 January 22 to September 1 with the Isaac Newton and William Herschel Telescopes. After correcting the observations for the recession velocity of M82 and for MilkyWay and host galaxy extinction, we measured expansion velocities from spectral line blueshifts and pseudo-equivalent width of the strongest features in the spectra, which gives an idea on how elements are distributedwithin the ejecta.We position SN 2014J in the Benetti, Branch et al. andWang et al. diagrams. These diagrams are based on properties of the Si II features and provide dynamical and chemical information about the SN ejecta. The nearby SN 2011fe, which showed little evidence for reddening in its host galaxy, is shown as a reference for comparisons. SN 2014J is a border-line object between the Core-normal and Broad-line groups, which corresponds to an intermediate position between low-velocity gradient and high-velocity gradient objects. SN 2014J follows the R(Si II)-Δm15 correlation, which confirms its classification as a relatively normal SN Ia. Our description of the SN Ia in terms of the evolution of the pseudo-equivalent width of various ions as well as the position in the various diagrams put this specific SN Ia into the overall sample of SN Ia. 2016 The Authors ; Published by Oxford University Press on behalf of the Royal Astronomical SocietyBased on service observations (programme SW2014a08) made with the WHT, and on discretionary and Spanish CAT service observations made with the INT, both operated on the island of La Palma by the ING in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofısica de Canarias. Support for LG and MH is provided by the Ministry of Economy, Development, and Tourism’s Millennium Science Initiative through grant IC120009, awarded to The Millennium Institute of Astrophysics, MAS. LG acknowledges support by CONICYT through FONDECYT grant 3140566. Support for MEMR and MM is provided by DGICYT grant AYA2010-21887-C04-02. This work is partially funded by DGICYT grant AYA2013-47742-C4-4-P. JIG-H, HL and JAR-M acknowledge financial support from the Spanish Ministry of Economy and Competitiveness (MINECO) under the 2011 Severo Ochoa programme MINECO SEV-2011-0187 JIG-H also acknowledge the 2013 Ramon y Cajal programme MINECO RYC-2013-14875, and the Spanish ministry project MINECO AYA2014-56359-P. EAC acknowledges the support of the STFC.Peer Reviewe

Efficacy and safety of urinary catheters with silver alloy coating in patients with spinal cord injury: a multicentric pragmatic randomized controlled trial. The ESCALE trial

PubMed ID: 28578163Background Patients with spinal cord injury (SCI) who carry indwelling urinary catheters have an increased risk of urinary tract infection (UTI). Antiseptic silver alloy-coated (SAC) silicone urinary catheters prove to be a promising intervention to reduce UTIs; however, current evidence cannot be extrapolated to patients with SCI. Purpose This study aimed to assess the efficacy of SAC urinary catheters for preventing catheter-associated urinary tract infections. Design/Setting This is an open-label, multicenter (developed in Spain, Portugal, Chile, Turkey, and Italy), randomized clinical trial conducted in 14 hospitals from November 2012 to December 2015. Patient Sample Eligible patients were men or women with traumatic or medical SCI, aged ?18 years, requiring an indwelling urinary catheter for at least 7 days. Outcome Measures The primary outcome was the incidence of symptomatic UTIs. The secondary outcome included bacteremia in the urinary tract and adverse events. Materials and Methods Patients were randomized to receive a SAC urinary catheter (experimental group) or a standard catheter (control group) for at least 7 days. Data were compared using chi-squared test and also calculating the absolute risk difference with a 95% confidence interval. An adjusted analysis including different risk factors of UTI was performed. This study was mainly funded by La Marató de TV3 Foundation (grant number # 112210) and the European Clinical Research Infrastructures Network organization. The funders had no role in the interpretation or reporting of results. Results A total of 489 patients were included in the study, aged 55 years in the experimental group and aged 57 in the control group (p=.870); 72% were men; 43% were hospitalized patients, and 57% were outpatients (p=1.0). The most frequent cause of SCI was traumatic (73.75%), and the localization was mainly the cervical spine (42.74%). Most of the patients had an A score (complete spinal injury and no motor and sensory is preserved) on the ASIA scale (62.37%). The median time of urethral catheterization was 27 days in the experimental group and 28 days in the control group (p=.202). Eighteen patients (7.41%) in the experimental group and 19 in the control (7.72%) group had a symptomatic UTI (odds ratio [OR] 0.96 [0.49–1.87]). The adjusted analysis revealed no change in the results. Only three patients in the experimental group had bacteremia within the urinary tract. The experimental group presented more adverse events related to the use of a catheter than the control group (OR 0.03 [0.00–0.06]). Conclusions The results of this study do not support the routine use of indwelling antiseptic SAC silicone urinary catheters in patients with SCI. However, UTIs associated to long-term urinary catheter use remain a challenge and further investigations are still needed. © 2017 Elsevier Inc.Fundació la Marató de TV3: # 112210 European Social Fund, ESF Instituto de Salud Carlos III, ISCIIIThe authors thank Mr. Ignacio Araya, who participated in the protocol development. This trial was funded by La Marató de TV3 Foundation , grant number # 112210 and the European Clinical Research Infrastructures Network (ECRIN, www.ecrin.org ). ECRIN reviewed the protocol, recruited Turkey and European centers, and submitted the clinical trial to the Ethics Committee (except in Spain) and, with these actions, partially supported the clinical trial. Bactiguard provided the study catheters with a 50% discount rate. This article has been written without financial support. Dr. María José Martínez-Zapata was funded by a Miguel Servet research contract from the Instituto de Salud Carlos III and the European Social Fund (Project no. CP15/00116 ). -